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《中国药房》网络版  2018 年 6 月第 2 期科普版                      Jun No.2 2018 China Pharmacy online Popular Science Edition



                   苗后并不意味着 100%安全,仍需定期筛查,及早发现及早干预。

                        总而言之,成功的 HPV 疫苗接种为全球女性提供了一顶强有力的保护伞,让

                   广大女性免于宫颈癌的威胁,但疫苗并非万能,只有尽力规避危险因素,才能离
                   癌症更远。



                   参考文献

                    International Human Papillomavirus Reference Center. Human

                   papillomavirus reference clones [EB/OL] [2018-01-25].

                   http://www.hpvcenter.se/html/refclones.htm.

                    de Martel C, Plummer M, Vignat J, et al. Worldwide burden of cancer

                   attributable to HPV by site, country and HPV type[J].Int J Cancer,

                   2017,141(4):664-670.

                    Joura EA,Giuliano AR,Iversen OE,et al.A 9-valent HPV vaccine against

                   infection and intraepithelial neoplasia in women[J].N Engl J

                   Med,2015.372(8):711-723.

                    Lehtinen M, Paavonen J, Wheeler CM, et al. Overall efficacy of
                   HPV-16/18 AS04-adjuvanted vaccine against grade 3 or greater cervical


                   intraepithelial neoplasia: 4-year end-of-study
                   analysis of the randomised, double-blind PATRICIA trial[J].Lancet Oncol,

                   2012,13(1):89-99.

                    Cameron RL,Kavanagh K,Pan J,et al.HumaJl papillomavirus prevalence

                   and herd immunitv after introduction of vaccination progmm,Scotland,

                   2009-2013 lJ].Emerg Infect Dis,2016,22(1):56-64.

                    程浩.预防性人乳头瘤病毒疫苗的新进展[J]. 中华皮肤科杂志,2017,50

                   (1):855-858

                   [7] Human papillomavirus vaccines: WHO position paper, May 2017[J]. Wkly

                   Epidemiol Rec, 2017,92(19):241-268.

                     European Medicines Agency.Cervarix,INN-Human Papillomavirus

                   Vaccine[Type 16, 18][EB /OL] [2016-08-18]. http: / /www.


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